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There are other trusted sources besides health-care professionals. If you are 
wading through the information on the Internet, stick to trusted sources like 
known universities—Yale, Harvard, the Mayo Clinic, or Johns Hopkins. 
There are also many 
research institutions like 
the National Institutes of 
Health, the National Cancer 
Institute, and the Muscular 
Dystrophy Association. 
There are professional 
organizations for every 
specialty, like the American 
Academy of Pediatrics and 
the American Academy of 
Neurology. There are also 
patient or disease advocacy 
groups like the Multiple 
Sclerosis Society. 

But there are also a lot of 
posers. Anyone can create 
a snazzy website and make 
it seem like they’re an 
impressive organization. 
Therefore, here are some 
red 

À

 ags to look out for: 

Beware of so-called institutes or organizations that seem to be doing nothing 
more than promoting a single individual. Beware of sites that seem to be 
trying to sell you something; they are probably distorting information to 
make that sale. Also, beware of outliers. If you’re visiting various sites 
that all seem to have one opinion, but Bob’s Institute of Syndrome X has a 
completely different opinion, it’s probably Bob’s Institute that you should 
be wary of. There are also well-meaning but misguided patient and disease-
oriented groups. There are groups that honestly want to do what’s best for 
patients, sufferers, and society, but they don’t have a culture of science. 

Don’t be afraid to ask questions of your health-
care providers.

© Hemera/Thinkstock.


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Lecture 1: Medical Knowledge versus Misinformation

Finally, there is no substitute for just thinking critically. At the end of the 
day, you have to think for yourself. Here are some more tips for reading 
information on the Internet: (1) If something sounds too good to be true, it 

probably is. If someone’s promising you 
the cure for cancer, you should be a little 
wary of that. (2) Don’t trust testimonials. 
They are just anecdotes, and as we say, 
the plural of anecdote is anecdotes, not 
data. Sites use testimonials to support 
their claims because they don’t have the 
scienti

¿

 c evidence to back them up. (3) 

Look for contrary information and opinions. If someone is trying to sell you 
a product, treatment, or therapy, speci

¿

 cally go out of your way to see what 

the critics of this are saying. (4) Finally, is there published, peer-reviewed 
evidence? That’s the ultimate currency of medical information. Having a 
peer-reviewed article is not a guarantee that the results will hold up over 
time or that they’re accurate, but it’s at least a good starting point. To search 
for this research yourself, go to the website PubMed.org. 

Over the next 23 lectures, we’re going to go on a journey together through 
many medical facts and myths. I will also discuss many controversial topics. 
Some of these topics may touch very close to home on beliefs that you 
have, and I ask you to listen with an open mind. My job is to go through 
the scienti

¿

 c literature, to try to make sense of the science as we understand 

it today. Sometimes that may lead to conclusions that are not necessarily 
popular or that are controversial. I also try to separate out real controversies 
within the scienti

¿

 c community itself from false controversies—ones where 

the scienti

¿

 c community is generally on the same page, but there are still 

public opinions that are contrary. I’ll also try to make clear when I’m giving 
you my own opinion or interpretation that may not be the de

¿

 nitive answer 

on a particular problem. 

Ŷ

The best source of 
reliable information is still 
health-care professionals.


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5

Note: Additional references for most lectures are listed at the end of 
the Bibliography.

Bausell, 

Snake Oil Science

.

Centers for Disease Control (website).

Ernst and Singh, 

Trick or Treatment

.

Mayo Clinic Online Reference. 

Sagan, 

The Demon-Haunted World

.  

Sampson and Vaughn, 

Science Meets Alternative Medicine

.

Science-Based Medicine

 (blog). 

1. 

How do we know which treatments are safe and effective for 
which conditions?

2. 

What role do you think informed consumers should play in their own 
health care?

    Suggested Reading

    Questions to Consider


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Lecture 2: Myths about W

ater and Hydration

Myths about Water and Hydration 

Lecture 2

So-called juicy foods like fruit contain a great deal of water, maybe 
60%–70%. There are some surprising foods, like a cooked hamburger, 
that have 40%–50% water.

A

bout 65% of the adult body by weight is made up of water. We all 
need water to survive, yet there are many misconceptions and much 
false information out there about this most basic element of life. 

How much water should we drink every day? If you are dehydrated, should 
you drink beverages with caffeine in them? Are expensive water puri

¿

 ers 

really worth it? 

The primary mechanism by which we maintain our hydration is thirst. 
Thirst is a powerful emotion that motivates us to eat and drink. Thirst 
actually serves two functions. First, it regulates the concentration of salt and 
other electrolytes in our blood—a property of the blood and tissues called 
osmolality. Also, it regulates the overall volume of water in our bodies. 
The other primary mechanism by which our bodies regulate our own 

À

 uid 

is urination. Many people ask how useful urine color is in determining 
our overall state of hydration. It turns out that it’s actually a pretty good 
rough marker. 

Another way our body loses water is through sweating. Sweating primarily 
is a mechanism to regulate body temperature, but it involves excreting saline 
from our sweat glands. In hot and dry environments or with physical activity, 
sweating can be a signi

¿

 cant source of water loss. This may dramatically 

increase the amount of 

À

 uid we need to drink in order to replace what we 

lose through sweat. 

One of the big myths of water is how much water we should drink every day. 
Typically, you’ll hear that you need to drink eight 8-ounce glasses of water 
per day. This myth probably originates from the Food and Nutrition Board, 
which calculated the average water needs of an average adult with average 
activity and environment and came up with the 

¿

 gure of 64 to 80 ounces per 


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7

day. However, in that same report, they also noted that most people get 20% 
of their 

À

 uid intake from food. Thus, even if you need 64 or 80 ounces, you 

don’t have to drink it all as water, and you don’t have to go out of your way 
to count up how many glasses of water you’re drinking. 

What about thirst myths? I’ve often heard that by the time you’re thirsty, 
it’s too late—you are already dehydrated. When you think about it, that 
doesn’t really make much sense, because thirst has evolved over millions 
of years to be a mechanism to tightly regulate how much 

À

 uid we need in 

our body. It wouldn’t work well if you didn’t become thirsty until after 

it was too late. In general, you 
can rely on your thirst. You will 
become thirsty long before you are 
actually dehydrated. Thirst works, 
and you don’t have to force 

À

 uid 

when you don’t feel like drinking. 

What about the myth that caffeinated 
drinks do not hydrate and in fact 
will make your hydration worse? 

This is based on a kernel of truth, as many myths are. Caffeine is a weak 
diuretic; therefore, if you drink a lot of caffeine, it could plausibly make you 
lose 

À

 uid. However, the diuretic effect of caffeine is actually very mild, and 

the 

À

 uid in most caffeinated beverages will more than compensate for this 

effect. If you’re out on a hot summer day and all you have is a caffeinated 
beverage to drink, go ahead and drink it. It will still hydrate you.

What about special situations in which we need to pay more attention to 
our hydration? In hot weather, we sweat more to cool ourselves off, and we 
therefore lose more 

À

 uid. Whenever you’re in a warm or hot environment, 

make sure you have access to 

À

 uid so that you can hydrate continuously. 

Fortunately, our bodies also acclimate to a hot situation by holding onto 
more 

À

 uid. Athletes often push human endurance to its limits, and water is 

no exception. Athletes can lose as much as 2 liters of sweat per hour. That 
means they may need to drink 12 liters of 

À

 uid in a day in order to just 

maintain their hydration. 

The diuretic effect of caffeine is 
actually very mild, and the 

À

 uid 

in most caffeinated beverages 
will more than compensate for 
this effect.