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Figure 2. Approach to the diagnosis of disorders of primary hemostasis

DIC = disseminated intravascular coagulation ATIII = antithrombin III

vWf = von Willebrand's factor

BLEEDING DISORDERS: DIAGNOSTIC APPROACH SIMPLIFIED

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Figure 3. Causes of disorders of secondary hemostasis

INHERITED

 

Factor I:

Hypo/dysfibrinogenemia (St. Bernards, Borzois)

II:Hypoprothrombinemia (Boxers)

VII:

Hypoproconvertinemia (Beagles, malamutes)

VIII:

Hemophilia A (numerous dog breeds, mongrels, cats)

IX:

Hemophilia B (numerous dog breeds, British shorthair cats)

X:Stuart Prower trait (Cocker spaniels)

XI:

Plasma thromboplastin antecedent deficiency (Springer spaniels, Great

Pyrenees)

 

XII:

Hageman factor deficiency (numerous dog breeds, cats)

ACQUIRED

-Vitamin K deficiency/antagonism

-Hepatic disease

-DIC

-Circulating anticoagulants (eg. heparin)

BLEEDING DISORDERS: DIAGNOSTIC APPROACH SIMPLIFIED

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Figure 4. Approach to the diagnosis of disorders of secondary hemostasis.

DIC = disseminated intravascular coagulation vWf = von Willebrand's factor

vWD = von Willebrand's disease

PIVKA = test for Proteins Induced by Vitamin K Absence/Antagonism

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BLEEDING DISORDERS: DIAGNOSTIC APPROACH SIMPLIFIED

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