Файл: Повышение неспецифической антиинфекционной резистентности у телятгипотрофиков биологическим и синтетическим иммуномодуляторами шахов А. Г., Сашнина Л. Ю., Ерина Т. А.doc
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тел.: (4732) 53-93-54, е-mail: L.Yu.Sashnina@mail.ru
Ерина Татьяна Анатольевна, аспирант отдела микробиологии, вирусологии и иммунологии, Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии; 394037, г. Воронеж, ул. Ломоносова, 114-б; тел.: (4732) 53-93-54, е-mail: vetfuck23@rambler.ru
Ответственный за переписку с редакцией: Шахов Алексей Гаврилович, доктор ветеринарных наук, профессор, член-корреспондент, заведующий отделом микробиологии, вирусологии и иммунологии, Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии; 394037, г. Воронеж, ул. Ломоносова, 114-б; тел.: . (4732) 53-93-54, е-mail: A.G. Shakhov@mail.ru
UDC:619:615.37:636.22/.28
NONSPECIFIC ANTI-INFECTIOUS RESISTANCE INCREASE IN CALVES WITH HYPOTROPHY TO BIOLOGICAL AND SYNTHETIC IMMUNOMODULATORS
Shakhov A.G., Sashnina L.Yu., Yerina T.A.
Summary
The researches made stated that immunodeficiency, detected in calves with hypotrophy during neonatal period, retained during the whole period of observation. Low adaptive potential connected with it was accompanied by instability of autarcesis rates that led to gastrointestinal and respiratory diseases with lingering and/or severe course. Immunomodulators were assigned to calves with hypotrophy during colostric period and promoted the formation of more evident adaptive immune response to antigenic impact during the period of immune system formation, that had a positive impact on clinical status of the animals.
Prolam and Immunofan usage is perspective for speeding-up the rehabilitation of the calves with antenatal hypotrophy, the increase of their immune status and resistance to gastrointestinal and respiratory diseases of the bacterial and viral-bacterial etiology.
Key words: calves with hypotrophy, resistance, Prolam, Immunofan, microbiocenosis, phagocytosis, bactericidal activity, complement, lysozyme.
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Author affiliation
Shakhov Aleksey Gavrilovich, Doctor of veterinary sciences, professor, corresponding member of the RAAS, head of Microbiology, Virology and Immunology Department, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394037, Voronezh, Lomonosova St., 114b; tel.: (4732) 53-93-54, е-mail: A.G. Shakhov@mail.ru
Sashnina Larisa Yuryevna, Candidate of veterinary sciences, key scientific associate of Microbiology, Virology and Immunology Department, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy; 394037, Voronezh, Lomonosova St., 114b; tel.: (4732) 53-93-54, е-mail:L.Yu.Sashnina@mail.ru
Yerina Tatyana Aleksandrovna, postgraduate student of Microbiology, Virology and Immunology Department, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy; 394037, Voronezh, Lomonosova St., 114b; tel.: (4732) 53-93-54, е-mail: vetfuck23@rambler.ru
Responsible for correspondence with the editorial board: Shakhov Aleksey Gavrilovich, Doctor of veterinary sciences, professor, corresponding member of the RAAS, head of Microbiology, Virology and Immunology Department, State Scientific Institution All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394037, Voronezh, Lomonosova St., 114b; tel.: (4732) 53-93-54, е-mail: A.G. Shakhov@mail.ru